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首页> 外文OA文献 >Patients with irritable bowel syndrome are more burdened by co-morbidity and worry about serious diseases than healthy controls- eight years follow-up of IBS patients in primary care
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Patients with irritable bowel syndrome are more burdened by co-morbidity and worry about serious diseases than healthy controls- eight years follow-up of IBS patients in primary care

机译：与健康对照组相比，肠易激综合症患者比健康对照者更易患合并症和担心严重疾病-八年IBS患者随访

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Background Irritable Bowel Syndrome (IBS) is a hidden public health disease that affects up to 20% of the general population. Although co-morbidity can affect diagnose setting and treatment of the disease, there are few studies concerning diagnosed and registered co-morbidity for IBS patients in primary care. The aim of this study was to analyse co-morbidity among IBS-patients compared to age- and sex-matched controls from the general population using data from a county-wide computerized medical record system. Methods IBS cases were recruited from three Swedish primary health care centres during a five-years period and controls from the same corresponding geographical areas. Co-morbidity data for IBS-patients and morbidity data for controls were derived from a population-based Health Care Register (HCR) covering all diagnoses in primary as well as hospital care in the region. Odds Ratios with 95% confidence intervals for morbidity in gastro-intestinal and non-gastrointestinal diagnoses for cases with irritable bowel syndrome compared to controls were calculated separately for each gender and diagnosis. Results We identified more co-morbidity among IBS patients of both sexes, compared to matched controls in the general population. Patients with IBS were particularly more worried about having a serious disease than their control group. The risk among male IBS-cases to get this latter diagnose was three times higher compared to the male controls. Conclusions In this population based case–control study, the analysis of diagnoses from the HCR revealed a broad spectrum of common co-morbidity and significantly more physician-recorded diagnoses among IBS-patients in comparisons to the control group.
机译：背景肠易激综合症（IBS）是一种隐性的公共卫生疾病，可影响多达20％的普通人群。尽管合并症可以影响疾病的诊断和治疗，但是很少有关于IBS患者在初级保健中诊断和注册合并症的研究。这项研究的目的是使用县范围内的计算机病历系统的数据来分析与来自普通人群的年龄和性别匹配的对照相比，IBS患者的合并症。方法在五年内从三个瑞典初级卫生保健中心招募IBS病例，并从相同的相应地理区域进行对照。 IBS患者的合并症数据和对照组的合并症数据均来自基于人口的卫生保健登记册（HCR），涵盖了该地区所有初级和医院诊断。分别针对每种性别和诊断分别计算了肠易激综合症患者与对照组相比在胃肠道和非胃肠道疾病中发病率的置信区间为95％的赔率。结果我们发现，与普通人群中的配对对照相比，IBS男女患病率更高。与对照组相比，IBS患者特别担心患有严重疾病。在男性IBS病例中，获得后者诊断的风险是男性对照的三倍。结论在这项基于人群的病例对照研究中，对HCR诊断的分析显示，与对照组相比，IBS患者中常见的合并症范围广泛，并且医师记录的诊断明显更多。

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